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von Thomas D. Pollard MD, William C. Earnshaw PhD FRS, Jennifer Lippincott-Schwartz PhD, Graham Johnson MA PhD CMI

Reader-friendly Cell Biology, 4th Edition, provides a concise but comprehensive foundation for students entering research or health care career paths. Award winning illustrations help readers quickly grasp general principles. The authors have thoroughly updated this popular text to provide readers with the current understanding of the principles of normal cellular function along with examples of how molecular defects predispose to human disease. Major new themes in the 4th edition include the roles of intrinsically disordered polypeptides and phase separation in cellular functions, the influence of new molecular structures on understanding mechanisms, and the impact of exciting new methods―from single cell RNA sequencing to second generation super resolution fluorescence microscopy―on advancing our understanding.Clear, readable explanations provide a concise story about how cells function at the molecular level.An intuitive chapter flow starts with genome organization, gene expression, and RNA processing as a foundation for understanding every aspect of cellular function and physiology.Brings cellular biology to life for students interested in medical science by explaining how mutations in genes can compromise virtually every cellular system and predispose to human disease. Knowledge of cell biology has led to new treatments for cancer, heart failure, cystic fibrosis, and many other diseases.Unique illustrations with realistic proportions and relationships explain every cellular process including the assembly of SARS CoV-2, the structures attaching mitotic chromosomes to microtubules, the mechanism of DNA replication and how pumps, carriers and channels orchestrate physiological processes from synaptic transmission to cellular volume regulation.Covers exciting breakthroughs such as SMC motor proteins actively organizing chromosomal DNA, TOR kinases regulating metabolism, new types of immunotherapy for cancer treatment, mechanisms regulating fast axonal transport and their relation to neurodegenerative diseases, how completion of DNA replication sets the time for cells to enter mitosis, how a cascade of signals specifies the site of cell division, and newly understood pathways of normal and pathological cell death.Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

von Nick Lane

If it weren't for mitochondria, scientists argue, we'd all still be single-celled bacteria. Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

von Steven G. Gabbe, Jennifer R. Niebyl, Joe Leigh Simpson, Mark B Landon, Henry L Galan, Eric R. M. Jauniaux, Deborah A Driscoll, Vincenzo Berghella, William A Grobman

After 30 Years, Obstetrics: Normal And Problem Pregnancies Remains Your Go-to Choice For Authoritative Guidance On Managing Today’s Obstetric Patient. International Experts Put The Latest Knowledge In This Specialty At Your Fingertips, With Current And Relevant Information On Everything From Fetal Origins Of Adult Disease, To Improving Global Maternal Health, To Important Topics In Day-to-day Obstetrical Practice. Highly Readable, Well-illustrated, And Easy To Understand, This Bestselling Obstetrics Reference Is An Ideal Tool For Residents And Clinicians. Take Advantage Of The Collective Wisdom Of Global Experts In The Field, Including Two New Editors— Drs. Vincenzo Berghella And William Grobman -- And Nearly 30 New Contributors. Gain A New Perspective On A Wide Range Of Today's Key Issues - All Evidence-based And Easy To Read. Sweeping Updates Throughout Including Four New Chapters: ‘vaginal Birth After Cesarean Delivery’; ‘placenta Accreta’; ‘obesity’; And ‘improving Global Maternal Health: Challenges And Opportunities’ New Glossary Of The Most Frequently Used Key Abbreviations For Easy Reference Expanded Use Of Bolded Statements And Key Points As Well As Additional Tables, Flow Diagrams, And Bulleted Lists Facilitates And Enhances The Mastery Of Each Chapter More Than 100 Images In The Obstetrical Ultrasound Chapter Provide An Important Resource For Normal And Abnormal Fetal Anatomy

von Dr. Robert Lustig

Paperback. Pub Date :2014-01-02 Pages: 336 Language: English Publisher: HarperCollins UK Sugar is toxic. addictive and everywhere So what chance do you have of living sugar-freeWith busy lives and little time left for cooking we find ourselves. relying on a diet of processed food But this is what's responsible for our chronically expanding waistlines. soaring levels of diabetes and a catalogue of diseases.Dr Robert Lustig reveals the truth about our sugar-laden food:. Why conventional low-fat weight loss advice won't work: not every calorie is the same. and skipping lunch doesn't mean it's ok to eat dessert Why too much sugar can cause serious illness even if you are not overweight How the food industry is filling our diets with hidden sugars - and which foods you must cut out to avoid themHow governments are complacent about. and even complicit in. exacerbating our food deb...

von Daniel Lieberman

'Endlessly fascinating and full of surprises. Easily one of my books of the year' BILL BRYSONThe myth-busting science behind our modern attitudes to exercise: what our bodies really need, why it matters, and its effects on health and wellbeing.In industrialized nations, our sedentary lifestyles have contributed to skyrocketing rates of obesity and diseases like diabetes. A key remedy, we are told, is exercise - voluntary physical activity for the sake of health. However, most of us struggle to stay fit, and our attitudes to exercise are plagued by misconceptions, finger-pointing and anxiety.But, as Daniel Lieberman shows in Exercised, the first book of its kind by a leading scientific expert, we never evolved to exercise. We are hardwired for moderate exertion throughout each day, not triathlons or treadmills. Drawing on over a decade of high-level scientific research and eye-opening insights from evolutionary biology and anthropology, Lieberman explains precisely how exercise can promote health; debunks persistent myths about sitting, speed, strength and endurance; and points the way towards more enjoyable and physically active living in the modern world.'Myth-busting, illuminating, brilliant - Lieberman will completely change the way you think about your body' Professor ALICE ROBERTS, presenter of Our Incredible Human Journey

von Aviva Romm

INSTANT NEW YORK TIMES BESTSELLER • WALL STREET JOURNAL BESTSELLER • #1 GLOBE AND MAIL BESTSELLER • USA TODAY BESTSELLER You are not broken. Being a woman is not a diagnosis. Take your body back with the groundbreaking new science for women in Hormone Intelligence. Hormonal. We all know what it means when we hear it – and feel it. While hormonal shifts are natural throughout women’s lives, too many experience distressing period symptoms, struggle daily with PCOS, endometriosis, a fertility challenge, pain, low sex drive, sleep problems, acne, bloating, hot flashes, and more – all due to hormone-related problems. And too many are unable to get the answers they’re really seeking from their doctors. There is a solution. In Hormone Intelligence, Yale trained and internationally renowned women’s health expert, Dr. Aviva Romm, helps you identify the root causes of your symptoms and guides you through a 6-week proven program to achieve lifelong hormonal and gynecologic health. Using a holistic, dietary and lifestyle changing approach, Hormone Intelligence goes beyond treating symptoms to the deeper factors impacting women’s health, so you can reclaim your body, hormones, and self. Inside Hormone Intelligence, you’ll find: ·       Hormone Health 101: Understand the key components of the hormone epidemic and associated dietary and lifestyle triggers. ·       Symptoms and Root Causes Demystified: Discover what your symptoms are saying about your hormones with quizzes, checklists, trackers, and more. ·       A 6-Week Action Plan: Learn what foods you should indulge and avoid, how to repair your microbiome to support hormone health, how to identify environmental hormone disruptors, engage your body’s natural detoxification systems and reduce hidden inflammation, and the lifestyle changes that lead to happy, healthy hormones. ·       Delicious, done-for-you meal plans to take you through the entire program, including vegan options. Hormone Intelligence is an invitation to a whole new relationship with your body and hormones, the exhale you’ve been waiting for, and the first step on the road to realizing that a diagnosis does not have to be your destiny. Extended references, a complete index, and additional resources for Hormone Intelligence can be found at the author's website. 

von Matthew Walker

Sleep is one of the most important aspects of our life, health and longevity and yet it is increasingly neglected in twenty-first-century society, with devastating consequences: every major disease in the developed world - Alzheimer's, cancer, obesity, diabetes - has very strong causal links to deficient sleep.Until very recently, science had no answer to the question of why we sleep, or what good it served, or why its absence is so damaging to our health. Compared to the other basic drives in life - eating, drinking, and reproducing - the purpose of sleep remained elusive.Now, in this book, the first of its kind written by a scientific expert, Professor Matthew Walker explores twenty years of cutting-edge research to solve the mystery of why sleep matters. Looking at creatures from across the animal kingdom as well as major human studies, Why We Sleep delves in to everything from what really happens during REM sleep to how caffeine and alcohol affect sleep and why our sleep patterns change across a lifetime, transforming our appreciation of the extraordinary phenomenon that safeguards our existence.

von Ben Carson M.D.

Gifted Hands reveals the remarkable journey of Dr. Ben Carson from an angry, struggling young boy with everything stacked against him to the director of pediatric neurosurgery at the Johns Hopkins Children's Center.As a boy, he did poorly in school and struggled with anger. If it were not for the persistence of his mother, a single parent who worked three jobs and pushed her sons to do their best, his story may have ended tragically.Join Dr. Carson on his journey from a struggling inner-city student to the pinnacle of his career as a world-renowned neurosurgeon. A man of humility, decency, compassion, courage, and sensitivity, he now serves as a role model for everyone who wants to achieve their God-given potential.As you learn more about Dr. Carson's amazing story, you'll be inspired to: Take charge of your own destiny Hone your God-given gifts Face adversity head on Filled with fascinating stories, Gifted Hands will transport you into the operating room to witness surgeries that made headlines around the world, and into the private mind of a compassionate, God-fearing physician who lives to help others.

von Carl Hart

High Price is the harrowing and inspiring memoir of neuroscientist Carl Hart, a leading researcher in the field of drug addiction, who grew up in one of Miami’s toughest neighborhoods and, determined to make a difference as an adult, tirelessly applies his scientific training to help save real lives. WINNER OF THE PEN/E. O. WILSON LITERARY SCIENCE WRITING AWARD Young Carl didn't see the value of school, studying just enough to keep him on the basketball team. Today, he is a cutting-edge neuroscientist—Columbia University’s first tenured African American professor in the sciences—whose landmark, controversial research is redefining our understanding of addiction. In this provocative and eye-opening memoir, Dr. Carl Hart recalls his journey of self-discovery, how he escaped a life of crime and drugs and avoided becoming one of the crack addicts he now studies. Interweaving past and present, Hart goes beyond the hype as he examines the relationship between drugs and pleasure, choice, and motivation, both in the brain and in society. His findings shed new light on common ideas about race, poverty, and drugs, and explain why current policies are failing.

von Jimmie C. Holland M.D et al.

Psycho-Oncology was the first comprehensive text in the field of psychosocial oncology and remains the gold standard today. Written by 67 internationally known psychiatry and palliative care experts, the resource is truly an essential reference for all providers of palliative care.Joining Oxford Medicine Online this resource offers the best quality content in an easy-to-access format. Online only benefits include downloading images and figures to PowerPoint and downloading chapters to PDF.