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von David Perlmutter MD
The bestselling author of Grain Brain uncovers the powerful role of gut bacteria in determining your brain's destiny.Debilitating brain disorders are on the rise-from children diagnosed with autism and ADHD to adults developing dementia at younger ages than ever before. But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In Brain Maker, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, Brain Maker opens the door to unprecedented brain health potential.
von Richard W. Wertz, Dorothy C. Wertz
This lively history of childbirth begins with colonial days, when childbirth was a social event, and moves on to the gradual medicalization of childbirth in America as doctors forced midwives out of business and to the home-birth movement of the 1980’s. Widely praised when it was first published in 1977, the book has now been expanded to bring the story up to date. In a new chapter and epilogue, Richard and Dorothy Wertz discuss the recent focus on delivering perfect babies, with its emphasis on technology, prenatal testing, and Caesarean sections. They argue that there are many viable alternatives―including out-of-hospital births―in the search for the best birthing system.Review of the first edition:“Highly readable, extensively documented, and well illustrated…A welcome addition to American social history and women’s studies. It can also be read with profit by health planners, hospital administrators, ‘consumers’ of health care, and all those who are concerned with improving the circumstances associated with childbirth.”―Claire Elizabeth Fox, bulletin of the History of Medicine“A fascinating, brilliantly documented history not merely of childbirth, but of men’s attitudes towards women, the effect of a burgeoning medical profession on our very conception of maternity and motherhood, and the influence of religion on medical technology and science.”―Thomas J. Cottle, Boston Globe“This superb book…is both an impeccably documented recitation of the chronological history of medical intervention in American childbirth and a sociological analysis of the various meanings given to childbirth by individuals, interested groups, and American society as a whole.”―Barbara Howe, American Journal of SociologyRichard W. Wertz, a builder in Westport, Massachusetts, is formerly an associate professor of American history at the Massachusetts Institute of Technology.Dorothy C. Wertz, is a research professor at the School of Public Health, Boston University
von Thomas D. Pollard MD, William C. Earnshaw PhD FRS, Jennifer Lippincott-Schwartz PhD, Graham Johnson MA PhD CMI
Reader-friendly Cell Biology, 4th Edition, provides a concise but comprehensive foundation for students entering research or health care career paths. Award winning illustrations help readers quickly grasp general principles. The authors have thoroughly updated this popular text to provide readers with the current understanding of the principles of normal cellular function along with examples of how molecular defects predispose to human disease. Major new themes in the 4th edition include the roles of intrinsically disordered polypeptides and phase separation in cellular functions, the influence of new molecular structures on understanding mechanisms, and the impact of exciting new methods―from single cell RNA sequencing to second generation super resolution fluorescence microscopy―on advancing our understanding.Clear, readable explanations provide a concise story about how cells function at the molecular level.An intuitive chapter flow starts with genome organization, gene expression, and RNA processing as a foundation for understanding every aspect of cellular function and physiology.Brings cellular biology to life for students interested in medical science by explaining how mutations in genes can compromise virtually every cellular system and predispose to human disease. Knowledge of cell biology has led to new treatments for cancer, heart failure, cystic fibrosis, and many other diseases.Unique illustrations with realistic proportions and relationships explain every cellular process including the assembly of SARS CoV-2, the structures attaching mitotic chromosomes to microtubules, the mechanism of DNA replication and how pumps, carriers and channels orchestrate physiological processes from synaptic transmission to cellular volume regulation.Covers exciting breakthroughs such as SMC motor proteins actively organizing chromosomal DNA, TOR kinases regulating metabolism, new types of immunotherapy for cancer treatment, mechanisms regulating fast axonal transport and their relation to neurodegenerative diseases, how completion of DNA replication sets the time for cells to enter mitosis, how a cascade of signals specifies the site of cell division, and newly understood pathways of normal and pathological cell death.Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
von Steven G. Gabbe, Jennifer R. Niebyl, Joe Leigh Simpson, Mark B Landon, Henry L Galan, Eric R. M. Jauniaux, Deborah A Driscoll, Vincenzo Berghella, William A Grobman
After 30 Years, Obstetrics: Normal And Problem Pregnancies Remains Your Go-to Choice For Authoritative Guidance On Managing Today’s Obstetric Patient. International Experts Put The Latest Knowledge In This Specialty At Your Fingertips, With Current And Relevant Information On Everything From Fetal Origins Of Adult Disease, To Improving Global Maternal Health, To Important Topics In Day-to-day Obstetrical Practice. Highly Readable, Well-illustrated, And Easy To Understand, This Bestselling Obstetrics Reference Is An Ideal Tool For Residents And Clinicians. Take Advantage Of The Collective Wisdom Of Global Experts In The Field, Including Two New Editors— Drs. Vincenzo Berghella And William Grobman -- And Nearly 30 New Contributors. Gain A New Perspective On A Wide Range Of Today's Key Issues - All Evidence-based And Easy To Read. Sweeping Updates Throughout Including Four New Chapters: ‘vaginal Birth After Cesarean Delivery’; ‘placenta Accreta’; ‘obesity’; And ‘improving Global Maternal Health: Challenges And Opportunities’ New Glossary Of The Most Frequently Used Key Abbreviations For Easy Reference Expanded Use Of Bolded Statements And Key Points As Well As Additional Tables, Flow Diagrams, And Bulleted Lists Facilitates And Enhances The Mastery Of Each Chapter More Than 100 Images In The Obstetrical Ultrasound Chapter Provide An Important Resource For Normal And Abnormal Fetal Anatomy
von Venki Ramakrishnan
"Utterly fascinating." —Bill Bryson"An incredible journey." —Siddhartha MukherjeeA groundbreaking exploration of the science of longevity and mortality—from Nobel Prize-winning molecular biologist Venki RamakrishnanThe knowledge of death is so terrifying that we live most of our lives in denial of it. One of the most difficult moments of childhood must be when each of us first realizes that not only we but all our loved ones will die—and there is nothing we can do about it.Or at least, there hasn’t been. Today, we are living through a revolution in biology. Giant strides are being made in understanding why we age—and why some species live longer than others. Could we eventually cheat disease and death and live for a very long time, possibly many times our current lifespan?Venki Ramakrishnan, recipient of the Nobel Prize in Chemistry and former president of the Royal Society, takes us on a riveting journey to the frontiers of biology, asking whether we must be mortal. Covering the recent breakthroughs in scientific research, he examines the cutting edge of efforts to extend lifespan by altering our physiology. But might death serve a necessary biological purpose? What are the social and ethical costs of attempting to live forever?Why We Die is a narrative of uncommon insight and beauty from one of our leading public intellectuals.
von Jacob Fidelis Ackermann
Journalist Beth Macy's definitive account of America's opioid epidemic "masterfully interlaces stories of communities in crisis with dark histories of corporate greed and regulatory indifference" (New York Times) -- from the boardroom to the courtroom and into the living rooms of Americans.In this extraordinary work, Beth Macy takes us into the epicenter of a national drama that has unfolded over two decades. From the labs and marketing departments of big pharma to local doctor's offices; wealthy suburbs to distressed small communities in Central Appalachia; from distant cities to once-idyllic farm towns; the spread of opioid addiction follows a tortuous trajectory that illustrates how this crisis has persisted for so long and become so firmly entrenched.Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy sets out to answer a grieving mother's question-why her only son died-and comes away with a gripping, unputdownable story of greed and need. From the introduction of OxyContin in 1996, Macy investigates the powerful forces that led America's doctors and patients to embrace a medical culture where overtreatment with painkillers became the norm. In some of the same communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, compelling, and unforgettably humane portraits of families and first responders determined to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows that one thing uniting Americans across geographic, partisan, and class lines is opioid drug abuse. But even in the midst of twin crises in drug abuse and healthcare, Macy finds reason to hope and ample signs of the spirit and tenacity that are helping the countless ordinary people ensnared by addiction build a better future for themselves, their families, and their communities."An impressive feat of journalism, monumental in scope and urgent in its implications." -- Jennifer Latson, The Boston Globe
von Rhiannon Lambert
A SUNDAY TIMES BESTSELLER--Is a vegan diet healthier? Should I try going low-carb? Is it always a bad idea to skip a meal? Are superfoods all they're cracked up to be? Is fat still bad for you? Can I eat to improve my chances of conceiving?Science of Nutrition cuts through the noise of conflicting diet advice with clear answers backed up by the very latest research.Recognising that there is no one-size-fits-all when it comes to nutrition, this ground-breaking book has the answers to all your food-related questions, covering every conceivable topic - from gut bacteria to weight management, to heart health and immune support, to vegan diets and intermittent fasting, and everything in between.With an accessible Q&A approach and informative graphics, this nutrition book will debunk popular food myths and diets, redefine nutrition in the modern world, and enable you to make informed decisions that are best suited to you, about what, when, and how to eat.The book's easily digestible and evidence-based advice empowers you to explore the benefits and importance of nutrition, alongside the downright misleading when it comes to the world of food and diet, and to equip yourself with the knowledge and confidence to assess and enhance your approach to nutrition.
von Ben Carson M.D.
Gifted Hands reveals the remarkable journey of Dr. Ben Carson from an angry, struggling young boy with everything stacked against him to the director of pediatric neurosurgery at the Johns Hopkins Children's Center.As a boy, he did poorly in school and struggled with anger. If it were not for the persistence of his mother, a single parent who worked three jobs and pushed her sons to do their best, his story may have ended tragically.Join Dr. Carson on his journey from a struggling inner-city student to the pinnacle of his career as a world-renowned neurosurgeon. A man of humility, decency, compassion, courage, and sensitivity, he now serves as a role model for everyone who wants to achieve their God-given potential.As you learn more about Dr. Carson's amazing story, you'll be inspired to: Take charge of your own destiny Hone your God-given gifts Face adversity head on Filled with fascinating stories, Gifted Hands will transport you into the operating room to witness surgeries that made headlines around the world, and into the private mind of a compassionate, God-fearing physician who lives to help others.
von Vincent M. Figueredo
Gold Award Winner, 2024 Nonfiction Book Awards Runner-up, 2024 History category, San Francisco Book Festival Runner-up, 2024 General Non-Fiction, New York Book Festival For much of recorded history, people considered the heart to be the most important organ in the body. In cultures around the world, the heart—not the brain—was believed to be the location of intelligence, memory, emotion, and the soul. Over time, views on the purpose of the heart have transformed as people sought to understand the life forces it contains. Modern medicine and science dismissed what was once the king of the organs as a mere blood pump subservient to the brain, yet the heart remains a potent symbol of love and health and an important part of our cultural iconography. This book traces the evolution of our understanding of the heart from the dawn of civilization to the present. Vincent M. Figueredo—an accomplished cardiologist and expert on the history of the human heart—explores the role and significance of the heart in art, culture, religion, philosophy, and science across time and place. He examines how the heart really works, its many meanings in our emotional and daily lives, and what cutting-edge science is teaching us about this remarkable organ. Figueredo considers the science of heart disease, recent advancements in heart therapies, and what the future may hold. He highlights the emerging field of neurocardiology, which has found evidence of a “heart-brain connection” in mental and physical health, suggesting that ancient views hold more truth than moderns suspect. Ranging widely and deeply throughout human history, this book sheds new light on why the heart remains so central to our sense of self.
von Amanda Ripley
It lurks in the corner of our imagination, almost beyond our ability to see it: the possibility that a tear in the fabric of life could open up without warning, upending a house, a skyscraper, or a civilization.Today, nine out of ten Americans live in places at significant risk of earthquakes, hurricanes, tornadoes, terrorism, or other disasters. Tomorrow, some of us will have to make split-second choices to save ourselves and our families. How will we react? What will it feel like? Will we be heroes or victims? Will our upbringing, our gender, our personality–anything we’ve ever learned, thought, or dreamed of–ultimately matter?Amanda Ripley, an award-winning journalist for Time magazine who has covered some of the most devastating disasters of our age, set out to discover what lies beyond fear and speculation. In this magnificent work of investigative journalism, Ripley retraces the human response to some of history’s epic disasters, from the explosion of the Mont Blanc munitions ship in 1917–one of the biggest explosions before the invention of the atomic bomb–to a plane crash in England in 1985 that mystified investigators for years, to the journeys of the 15,000 people who found their way out of the World Trade Center on September 11, 2001. Then, to understand the science behind the stories, Ripley turns to leading brain scientists, trauma psychologists, and other disaster experts, formal and informal, from a Holocaust survivor who studies heroism to a master gunfighter who learned to overcome the effects of extreme fear.Finally, Ripley steps into the dark corners of her own imagination, having her brain examined by military researchers and experiencing through realistic simulations what it might be like to survive a plane crash into the ocean or to escape a raging fire.Ripley comes back with precious wisdom about the surprising humanity of crowds, the elegance of the brain’s fear circuits, and the stunning inadequacy of many of our evolutionary responses. Most unexpectedly, she discovers the brain’s ability to do much, much better, with just a little help.The Unthinkable escorts us into the bleakest regions of our nightmares, flicks on a flashlight, and takes a steady look around. Then it leads us home, smarter and stronger than we were before.